2-4 Hours: 5-HTP is a nutritional precursor to serotonin. It should not be taken with many antidepressants. It has a relatively short half-life of 2-4 hours and 75mg is not a very large dose. Anyone who feels they had a negative reaction to that small of a dose should not take more and should consult with someone who can help go over the reasons why you think you need 5-HTP and help you further.
Answered 4/21/2016
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