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A member asked:

Recently started 10mg methotrexate for lupus. completed 2 doses. began having extreme fatigue, clay colored stools, indigestion. what can cause this?

3 doctors weighed in across 2 answers
Dr. Hamsa Jayaraj answered

Specializes in Internal Medicine

Talk to prescriber: These are side effects of methotrexate. Google for all the side effects of methotrexate.

Dr Chuu agreed

Answered 11/27/2017

1.4k views

Thank
Dr. Eric Chiang answered

Specializes in Rheumatology

Unlikely related to: Methotrexate, but will recommend to discuss with your rheumatologist and likely will need evaluation for your liver, gallbladder, and possible GI tract.

Answered 10/22/2017

1.4k views

Thank

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Can methotrexate help with mild vasculitis of brain/cerebritis or neuro symptoms caused my ctd such as lupus?

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Might methotrexate help w/dysautonomia symptoms caused by autoimmune disorder like lupus when standard tx (floninef & salt)don't' work but prednisone does?

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Methotrexate :The most common adverse effects include: hepatotoxicity (liver damage),but could this be seen in low dose for Lupus affecting skin ?

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Tired Muscle twitches, blood in stool sometimes and in urine. Lost 20 lb in 18 months. All imaging and ultrasound are good. Doc thinks lupus? Correct?

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A member asked:

Which is safer (less longterm risks) to use long term for lupus control: prednisone 5mg daily or methotrexate weekly? (i'm also on plaquenil).

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