A 35-year-old member asked:
Can peptic ulcer disease lead to cancer?
2 doctor answers • 5 doctors weighed in
Dr. Gurmukh Singhanswered
Pathology 51 years experience
Rarely: Peptic ulcers and stomach cancer are both caused, in part, by helicobacter infection. A stomach cancer may present as an ulcer. A bona fide peptic almost never turns into cancer.
Created for people with ongoing healthcare needs but benefits everyone.
5.2k viewsReviewed >2 years ago
Dr. Shaban Faruquianswered
Specializes in Gastroenterology
Hp -Pud-CA in some: H. pylori infection can lead to chronic gastritis, atrophy of mucosa, and fibrosis with intestinal metaplasia, this change increase risk of Cancer, in addition genetic susceptibility contributes.H.pylori is strongly linked to gastric cancer and is now classified as a group I carcinogen.Of interest H. pylori infection may protect against esophageal adenocarcinoma through reduction in gastric acid
Created for people with ongoing healthcare needs but benefits everyone.
194 viewsReviewed >2 years ago
Dr. Shaban Faruqui commented
Specializes in Gastroenterology
Provided original answer
Gastric ulcer disease and gastric cancer have etiologic factors in common. A likely cause of both is atrophic gastritis induced by H. pylori. By contrast, there appear to be factors associated with duodenal ulcer disease that protect against gastric cancer.Helicobacter pylori infection is now recognized as an important causative factor in both duodenal ulcers and gastric cancer.
Apr 5, 2019
Last updated Apr 6, 2019
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