A member asked:

Can peptic ulcer disease lead to cancer?

5 doctors weighed in across 2 answers
Dr. Gurmukh Singh answered

Specializes in Pathology

Peptic ulcers and stomach cancer are both caused, in part, by helicobacter infection. A stomach cancer may present as an ulcer. A bona fide peptic almost never turns into cancer.

Answered Oct 16, 2017

5.2k views

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Dr. Shaban Faruqui answered

Specializes in Gastroenterology

H. pylori infection can lead to chronic gastritis, atrophy of mucosa, and fibrosis with intestinal metaplasia, this change increase risk of Cancer, in addition genetic susceptibility contributes.H.pylori is strongly linked to gastric cancer and is now classified as a group I carcinogen.Of interest H. pylori infection may protect against esophageal adenocarcinoma through reduction in gastric acid

Answered Apr 6, 2019

194 views

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