A member asked:
i took 25 grams of sertraline and 20 grams of paxel then took some off brand nyquil that contains dm, should i be worried?
3 doctor answers
Dr. William Haehl answered
45 years experience Family Medicine
Doubtful: You will probably not have any problems except for increased drowsiness more from the NyQuil. But in general do not mix drugs like those. Sertaline and Paxil (paroxetine) are very similar drugs so I'm not sure why you would be on both of those. Talk to your doctor.
Answered on Mar 15, 2016
Dr. Edward Kuhnley answered
44 years experience Child Psychiatry
Some Nyquil preps: contain Dextromethorphan cough suppressant which interacts with sertraline and paxil (paroxetine) (which are serotonin antidepressants - only one of them is necessary at a time). It increases risk of a rare but serious condition called serotonin syndrome (http://www.mayoclinic.org/diseases-conditions/serotonin-syndrome/basics/symptoms/con-20028946). Consult your prescriber to clarify TX. Best regards.
Answered on Apr 20, 2016
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