Seroquel (quetiapine): can cause akathisia, although it is rare. It's been reported in the literature especially in patients who are particularly prone to developing what's called "extrapyramidal" or this type of uncomfortable restless side effect.
Answered 1/28/2019
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Yes: Akathisia may occur in 1% to 10% of people taking Seroquel. REF: https://www.drugs.com/sfx/seroquel-side-effects.html
Answered 7/5/2020
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