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A 25-year-old female asked:

Is a mono relapse possible? my boyfriend and i both had it last year and are experiencing the same symptoms again this year

2 doctor answers5 doctors weighed in
Dr. Christine Hom
Pediatrics 30 years experience
Mononucleosis: Once infected, mono stays in your body. You don't contract mono a second time, although some of the symptoms are common and nonspecific, like fatigue, sore throat, muscle or joint aches. Probably this is not mono.
Dr. Christine Hom
Pediatrics 30 years experience
Provided original answer
Feb 14, 2016
Dr. Christopher Conti
Specializes in Emergency Medicine
MONO-e-MONO: Yes, either one or both of you could have a re-acquired mononucleosis. If you are concerned, you can be tested. I would be happy to arrange these test for you with a Concierge Consult appointment. Thanks for trusting HealthTap with your care & questions.

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Last updated Nov 20, 2017

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