A member asked:

If my grandma and i have down syndrome, but my parents don't, can my child have down syndrome?

3 doctors weighed in across 2 answers

Yes: Down syndrome can occur in families without a history of down syndrome. Fertility is difficult with Down syndrome due to the chromosomal anomaly and your future offspring will be at at risk. Discuss this in detail with a genetic counselor before attempting to get pregnant.

Answered 2/18/2015

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Confusing question: Certainly women with Down syndrome are fertile, achieving puberty at the same time as most of their age group.They can have infants that are both normal and have down syndrome. The question is an articulate one, more so than some of the physician answers. You appear to be stating ds skipped a generation in your family.Unless yours is a mosaic form, i doubt you are ds, ?Who is writing this?

Answered 2/18/2015

4.9k views

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