Not on omeperazole: It is not recommended to take pepcid while on omeperazole as there is duplication of therapy or effect. They both decrease production of gastric acid although through different mechanisms. However, having mitral valve prolapse does not pose any specific reason why one could not take pepcid or any other h2 blocker such as zantac, (ranitidine) pepcid etc.
Answered 4/23/2016
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