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A 84-year-old female asked:

is it safe to use valproic acid in pregnancy?

2 doctor answers6 doctors weighed in
Dr. Heidi Fowler
Psychiatry 25 years experience
Not recommended: This FDA Pregnancy Category D - so it isn't recommended. It can be associated with risk for significant risks to the fetus.
Dr. Matthew Smith
Psychiatry 40 years experience
No.: It is highly associated with fetal malformations (neural tube defects). However, to give a thorough answer, I have heard of women taking it during pregnancy and supplementing with large amounts of folic acid. Don’t try this without an informed obstetrician, though, and think very hard about doing it.

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Last updated Nov 28, 2017

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