Oxycodone/fluoxetine: oxycodone will increase the level/effect of fluoxetine (affects enzyme CYP2D6 metabolism). Possible serious or life-threatening interaction. Monitor closely. Use alternatives if available. Opioids may enhance the serotonergic effects of SSRIs and increase risk for serotonergic syndrome. Oramorph is morphine. Talk with prescriber to review how meds affect you. Best regards for relief.
Answered 11/10/2015
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