A member asked:

Does the brain return to normal after using zoloft (sertraline)? do serotonin receptors regrow?

5 doctors weighed in across 2 answers

Do not fret: Once Zoloft (sertraline) is stopped and out of your system, the brain responses revert to baseline functioning, and no lingering problems will persist. The seratonin receptors are NOT damaged by Zoloft (sertraline), their functions are merely altered beneficially while the drug is present, and they too return to physiological functioning.

Answered 6/15/2019

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Varies: When depressed, serotonin receptors are typically modified. Sertraline helps to restore receptors to how they are when you are not depressed. When sertraline is stopped, the response is variable, depending on many things. For some, the receptors remain as they have been on sertraline, and one is not depressed; for others, they revert to the depressed condition, and one reverts to depression.

Answered 6/15/2019

2.1k views

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