Will clobetasol propionate help with male jock itch?

No will make worse: Jock itch is a fungal infection needing to be treated by antifungal medication. Clobetasol is a steroid. It suppresses the immune system so it will make fungal infections much worse. It is useful in genital skin disorders caused by inflammation -- things like eczema. Consider a virtual visit with a healthtap primary care doctor and attach an image of the affected area. Correct diagnosis required

Not a good treatment: "Jock itch" is not a diagnosis. There are dozens of possible causes for genital itch. Begin with a specific definition of the cause. Successful treatment flows from that. Clobetasol, as a super-potent steroid, is prone to cause ugly, annoying purple streaks and thin, wrinkled skin when used on the genital skin. Avoid use in this area for more than a few days.