1st time on 150mg of sertraline it worked well. now it's my 2nd but i can't feel the same benefits at all. you think an increase in dose is required?

Major Depression: I understand your concern about “can’t feel same benefits at all” from Sertraline 150mg/day. Sertraline 150mg/day is high Dose. Increasing the dose further can have serious side effects. See a Psychiatrist to establish Diagnosis, benefits and side effects of medications for depression and anxiety, dose; and Therapy for stresses of relationships, unresolved conflicts, work and finances