Can i take omeprozole for nighttime gerd if i'm taking alendronate 70mg once a week? don't the two work opposite in regard to calcium?

See answer below: Given your age and likelihood of having osteoporosis as you are on fosamax, (alendronate) you should check with your doctor about the need for omeprazole. Perhaps there's something you can change in your diet (ie, reduced caffeine intake) and lifestyle (exercise, cutting out midnight snacking) that can be done to reduce heartburn frequency.