That's a lot: Taking 25 mg of Benadryl (diphenhydramine) will be like having consumed 1-2 extra oz of whiskey in term of drowsiness effect. If you have previously consumed 6 oz of whiskey without problem, this may be ok. However if you had never drunk this much, then I would be cautious with the Benadryl (diphenhydramine).
Answered 11/8/2020
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