A member asked:

How long after taking 50mg benadryl (diphenhydramine) is it safe to drink alcohol?

A doctor has provided 1 answer
Dr. John Chiu answered

Specializes in Allergy and Immunology

The drowsiness effect from Benadryl (diphenhydramine) varies from one person to another. Although the antihistaminic effect may last for over a day, the drowsiness effect is likely less than 6 hrs. Alcohol just makes the drowsiness worse.

Answered Feb 9, 2021

4.2k views

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Is Benadryl (diphenhydramine) 25mg and 2 alcohol drinks safe?

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