C Diff and PPI's: There is a moderate amount of evidence that C. difficile infection is more common in PPI users. You can try H2 blockers, such as Zantac, (ranitidine) but if your symptoms persist unabated, your physician will need to decide whether the symptoms you're having outweigh the increased risk of C. difficile infection. If your doctor agrees, try Zantac, (ranitidine) but you may need to have this discussion with him. Good luck.
Answered 9/20/2015
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