Does flonase have systemic effects?

Not really: If you use only as prescribed , you are safe. I tell my pts give a break on the weekends or donot use on 2 nights a week. Spray on nasl wall only i.E r side with l hand and vice versa.

Negligible to none: Absorption of Flonase if used at the recommended dose is minimal. There were no significant long term adverse effects with the studies. With any nasal steroids, long term use is not advised. Always consult your dr for any concerns or questions.