A member asked:

How can blighted ovum happen after pgs testing? i have mthgr gene one but doctor only gave baby aspirin. could this be cause?

A doctor has provided 1 answer
Dr. Richard Roberts answered

Specializes in Pediatrics

Mosaicism, bad luck: A blighted ovum is a gestational sac without development of an embryo. Aspirin cannot kill a developing embryo, so eliminate that idea. When they test the blastomere for a normal chromosomal compliment, they test only one cell. Very rarely, mitotic nondisjunction can occur, perhaps during blastomere stage, and the embryo may form from that cell lineage, which might cause so much trouble it dies.

Answered 8/13/2015

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