A member asked:

What are the advantages/disadvantages of imiqunoid vs surgical excision to treat differentiated vin 2?

2 doctors weighed in across 2 answers

I'd opt for surgery: http://www.ncbi.nlm.nih.gov/pubmed/23640441 There are various studies with various conclusions but if it were my own wife, I'd still feel most comfortable with surgery and a good pathology exam of the specimen.

Answered 8/12/2015

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Dr. Georgia Latham answered

Specializes in Family Medicine

Imiquimod 5%: offers a noninvasive treatment for VIN. A major advantage over the potential scarring, deformity, and/or recovery from surgery. It provides complete resolution in ~75% cases. There is a ~25% risk of disease recurrence. Imiquimod works by prompting your immune system to fight the cancer. The inflammatory response to imiquimod can result in topical side effects, requiring breaks in treatment.

Answered 8/12/2015

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