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A member asked:
I take 150 mg. amitriptyline at night for anxiety and depression. does drinking caffeine takes away the benefits of the medication?
9 doctors weighed in across 4 answers
No : No , but not more than one drink or two.
Answered 4/25/2016
5.2k views
Anxious moments: It certainly may nullify the effect of the medications.
Answered 4/11/2013
5.2k views
Could be: If you're drinking caffeine at night, it could make you anxious and jittery -- temporarily anyway. It would not nullify the overall effects of amitriptylene as an antidepressant, but might make you nervous & harder to go to sleep. If you must drink caffeine, i'd suggest doing it in the morning, and none after noon or so. Anxious people probably don't need it at all, though!
Answered 12/9/2013
5.2k views
Can add to anxiety: Caffeine doesn't alter the antidepressant effect of Elavil (amitriptyline), but it can cause or worsen anxiety. So in that sense it could counteract the effect of the medication. Low to moderate amounts of caffeine shouldn't be a problem unless you're fairly sensitive to it, but on general principles i advise anxious patients to minimize caffeine.
Answered 4/17/2016
5.2k views
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