How long does it take for mifegyne to work? i took it at 1pm yesterday still no bleeding

24-48 hours but...: it's very important that you take the follow up medication, a prostaglandin, to stimulate your uterus to contract so that it will expel everything. These drugs, alone or in combination, aren't 100% safe & effective. It's very important for your current health and future ability to bear children that you get the necessary follow up. Best wishes to you.