Pakistan
A 23-year-old female asked:

High cortisol level in evening , high acth level131pg...mild hypertension.., no mass in suprarenal gland , cuahing appearance..cause?

1 doctor answer1 doctor weighed in
Dr. Alan Feldman
43 years experience
Possible pituitary: Having a high cortisol with a high acth level is indicative of acth dependent cushings disease. This is a rare disorder due to a pituitary adenoma making too much acth. You may or may not be able to see an abnormality on ct scan or MRI of the pituitary. You should do Dexamethasone suppression testing to confirm the diagnosis. Sometimes the acth is coming from a source outside of the pituitary.
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Last updated Jun 25, 2014

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