What are the direct effects of taking aleve (naproxen) with melocicam? i am aware they are both nsaids but what is the worst result?

Overdose?: Any medication (or meds in the same class) when taken in excess can cause problems. It depends on the amount and how often you are doing it and what your other medical problems may be. How much did you take? Did you do this on purpose? Is so, call 911. If you took more than the recommended dose of either, call poison control to find out how serious it is and what to expect/do.