Can taking penicillin 500mg, twice a day for 20 days or so cure toenail fungus?

Not an easy Fix.: A thousand milligrams of penicillin a day for 20 days will probably kill a lot of things, but, it will have no effect on the fungus. The treatment of nail fungus can range from topical solutions to oral anti-fungal medications and everything in between. There is also an array of homeopathic remedies and treatment protocols. Laser treatment is being used and the results look promising.

Toenail fungus: There is no way that penicillin can cure fungus! I should never say never to anything, but this would be biggest breakthrough in medicine since penicillin was even discovered. Sorry, this won't work. Unfortunately the mechanism of action for antibiotics will have no affect on toenail fungus. There are safe and effective treatments for toenail fungus. Check with your local podiatrist.