Does metformin lead to low levels of vitamin d3 or vitamin b over time?

Low B12 possible: Metformin can cause the body to become depleted of vitamin b12. Often, an non-prescription supplement can correct this, but it is always a good idea to get a level checked to see if you need a supplement before you start taking one.

Can lower b12: After several years on metformin, populations at risk of B12 deficiency such as the elderly (as they r more at risk for atrophic gastritis) might develop B12 deficiency- simple blood test to confirm. Easy to treat: B12 pills. Usu. Ppl on metformin get a lot more benefit from med than harm, even if they get B12 deficiency.

Vit B12 & others: In addition to depletion of vit b12, metformin has also been shown to deplete levels of Folic Acid and coq10 enzyme.

No and yes: Metformin does not lower vitamin d, but people with diabetes and people who are overweight are at increased risk if vitamin d deficiency. Metformin can cause b 12 deficiency.