A 72-year-old female asked:
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Can high levels of bilirubin alone cause liver failure in a metastic liver cancer pt?

1 doctor answer
Dr. Jan Lei Iwata
25 years experience in Ophthalmology
It's usually the : result of liver failure,bnot the cause of liver failure.In metastatic disease to the liver, the hepatocytes are no longer working properly in conjugating the free bilirubin, so it's backing up & accumulating. Serum bilirubin is considered a true test of liver function, as it reflects the liver's ability to take up, process, and secrete bilirubin into the bile. This is compromised in liver mets.
Answered on Jun 22, 2015
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Dr. Herman Hammerstead
49 years experience in Trauma Surgery
The TRUE Liver functions test are the products made by the liver. Pro-time and Albumin are the only true liver functions........Telfer Reynolds, MD
Jun 22, 2015

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A 72-year-old female asked:
Dr. Thomas Mcgowan
Specializes in Family Medicine
Bilirubin: the high bilirubin will not cause death in this situation, it likely is a sign that the bile ducts are blocked up by metastatic cancer in the liver.
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A 72-year-old female asked:
Dr. Robert Uyeda
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Depends on: level of bilirubin, but in general metastatic cancer has a poor prognosis. Isolated bilirubin elevation can be caused by obstruction or hemolysis. C ... Read More
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A 72-year-old female asked:
Dr. Julie Abbott
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High bilirubin..: ..in the blood causes jaundice..the yellowish discoloration of the skin, mucous membranes and whites of the eyes. Trying to stall the cancer with chem ... Read More
A 72-year-old female asked:
Dr. Harold Fields
60 years experience in Family Medicine
Liver: No I do not think it is the liver failing. I think it is. sign of liver involvement in the metastaticc process
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