What is the difference between depakote and lamictal?

Anticonvulsivants: Both Lamotrigene and Valproate are anticonvulsant agents. They have similar actions, mostly sodium channel blockers. Some of the differences are: Valproate is metabolized in the liver, its blood level can be measured, it is more effective in manic states but not depression. Lamictal has to be increased gradually, is effective in depression, and linked to Steven Johnson syndrome, a serious skin dis