U.S. doctors online nowAsk doctors free
A 27-year-old female asked:

I have hypothyroidism & on thyronorm 100mcg...can we take the medicine before bed at night rather than early morning?? will it reduce absorbing power?

2 doctor answers2 doctors weighed in
Dr. Alvin Lin
Geriatrics 32 years experience
Hypothyroidism: Great question! We recommend taking Levothyroxine on an empty stomach (2hrs before or after eating/drinking). However, some studies suggest better results if taken right before bedtime, presumably on empty stomach, too. As long as you're consistent & taking same time 24hrs apart, you should be fine. Tell prescribing doc that you're going to change timing & ask to recheck TSH in 6wks to be safe.
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Alvin Lin
Dr. Alvin Lin commented
Geriatrics 32 years experience
Provided original answer
Check out Arch Intern Med. 2010;170(22):1996-2003 Also Clinical Endocrinology (2007)66, 43–48
May 18, 2015
Dr. John Goldman
Rheumatology 57 years experience
Absorption can be less: absorption can be less. If you take it every night on a regular basis. When you do this for an extended basis then your thyroid levels will stabilize and then your physician can adjust. Absorption can vary though and you will need periodic monigoring.
Created for people with ongoing healthcare needs but benefits everyone.
Last updated May 18, 2015


Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.