A member asked:

Is 34% of sperm dna fragmentation high to achieve natural pregnancy?

4 doctors weighed in across 2 answers

It depends: A good DNA fragmentation Index (DFI) should be less than 15%. But when the DFI is between 25-50% than the integrity of sperm DNA is fair to poor. Any thing >30% IVF would help. But if you want a natural pregnancy it might be difficult at this percentage. But it is not impossible just harder. I would you speak with your fertility specialist regarding what your options would be. Good Luck :)

Answered 5/17/2015

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Dr. Brian Nguyen answered

Specializes in Obstetrics and Gynecology

Consult needed: There are too many factors involved in a natural pregnancy to give you an answer. Sperm DNA fragmentation is only a fragment and although 34% is abnormal (fair quality), it does not mean that you can't have a normal pregnancy as this number is a point in time and can be altered by many factors, i.e. smoking, infection, varicocele, environmental exposures, diet, etc.

Answered 2/27/2017

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