Many things: Systemic inflammation (acute infection, autoinflammatory diseases such as lupus or rheumatoid arthritis), stress (emotional or physical), hypersensitivity to pain or abnormal pain suppression pathways (fibromyalgia), joint abnormalities (connective tissue diseases such an Marfan syndrome or Ehler-Danlos syndrome), blood disorders (anemia, leukemia) and many more. Would need more info to fine tune.
Answered 4/29/2015
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A doctor has provided 1 answer
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