RLS cause unknown: We do not know the cause of most cases of restless legs syndrome. However, low iron stores can cause it. So can neuropathies (nerve problems), kidney disease, spinal cord injuries. In most cases there is no known cause.
Answered 10/23/2013
6.1k views
A few things: Genetics is major contributor. Also medical issues and medication. Low iron, low b12, overactive thyroid, low folate (folic acid) and kidney problems. Medications, including antihistamines, antidepressants, stimulants (caffeine/tobacco) and Dopamine antagonists can also cause.
Answered 2/2/2017
5.7k views
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