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A 41-year-old female asked:

Can i take benadryl (diphenhydramine) and sudafed while taking wellbutrin?

2 doctor answers6 doctors weighed in
Dr. Sophie Duriez
Psychiatry 32 years experience
No : All these medications are known to raise blood pressure. Check with your primary care physician what is the best treatment for you. Avoid self-medicating! Good luck and keep your health the best way possible
Dr. Georgia Latham
Family Medicine 35 years experience
Not sudafed: It is okay to take benadryl (diphenhydramine) while taking Wellbutrin, although a less sedating anti-histamine such as Claritin or Zyrtec might be a better choice. Sudafed can result in increased heart rate and/or blood pressure, and these effects may be worsened while taking Wellbutrin. Try taking guafenesin in the form of Robitussin or Mucinex, it is very safe and may be very helpful for your congestion.
Dr. Sophie Duriez
Psychiatry 32 years experience
Dr. Latham, unless you had more information about "Brandon900", than I did, with all due respect, I think it is taking a risk to recommend medication and treatment without vitals and clinical exam data.
Apr 11, 2015

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A 39-year-old member asked:

What's the difference between Benadryl (diphenhydramine) and sudafed?

1 doctor answer1 doctor weighed in
Dr. David Martin
ENT and Head and Neck Surgery 28 years experience
Medical questions: Benadryl (diphenhydramine) is an antihistamine, good for allergies and to lessen the drainage during an upper respiratory infection. Sudafed is a decongestant, good for helping you breath through a stuffy nose from a cold, bad allergies or sinus problems. Sudafed can also raise blood pressure, and shouldn't be taken on a regular basis.

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Last updated Nov 28, 2017

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