It depends: The classic Huntington disease causing genetic mutation is ALWAYS familial, BUT paternity is NOT always known or a parent may have died before the disease is manifest, so it may appear sporadic. There is a rare HD-like mutation that behaves just like classic HD, but represent a different abnormal area on the genome. This one is also not thought to arise sporadically and the same caveats apply
Answered 4/2/2015
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Huntington's: Genetic, with Autosomal dominant transmission.
Answered 5/3/2015
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