I got my first dose of depo on jan 31st n my 2nd shot is due may 2nd.is it normal to have orange blood spotting and it's only when i wipe.

Not unusual: You have chosen a very effective way to prevent pregnancy which will also cause some changes in your menstrual cycles. You may spot, stain or bleed irregularly particularly after the first 2 or 3 injections or not bleed at all after a few months. The progestin hormone in "depo" blocks your ovulation and at same time causes the lining of your uterus to become thinner, bleed intermittently or not bl