HealthTap Online Primary Care Doctors Accepting New Patients
Book a video visit
HealthTap
Telehealth
A member asked:

I have a bad cold and a sinus infection. i just took 2 tblespoons of nquil. can i take a benadryl (diphenhydramine) also?

A doctor has provided 1 answer
Dr. Al Hegab answered

Specializes in Allergy and Immunology

Better no: Nyquil has an antihistaminil in its components, so don't add benadryl, (diphenhydramine) fluids and rest should be your remedies for now, see urgent care in the morning if not improved, goodluck

Answered 3/14/2015

3.1k views

Thank

Related Questions

A member asked:

Can you take Benadryl (diphenhydramine) with Advil cold and sinus?

A doctor has provided 1 answer

A member asked:

Can you take Advil cold & sinus with benadryl (diphenhydramine) & a clartin?

A doctor has provided 1 answer

A member asked:

I am 19 weeks pregnant and took one benadryl (diphenhydramine) tablet for sinus infection. About 2 hours later I almost had two anxiety attacks along rapid heartbeat?

A doctor has provided 1 answer

A member asked:

I took 2 Excedrin tension pills.. Can I take 2 Benadryl (diphenhydramine) sinus headache on top of that?

A doctor has provided 1 answer

A member asked:

Can Benadryl (diphenhydramine) be taken 2 hours after Advil cold sinus?

A doctor has provided 1 answer

Sponsored Content
HealthTap Medical Group does not endorse products or services. Sponsored content revenues support our mission to make health information free and accessible to all.Learn more

People also searched for:

I recently got a sinus infection about 2 days ago. I've been taking Benadryl (diphenhydramine) for it. Its the third day and my entire body hurts and I have a cough.
I was taking Amoxicyllin to treat a sinus infection. After a week of use, I just developed a terrible rash. My torso & back are covered. Benadryl (diphenhydramine)?
Can you take Benadryl allergy with Mucinex Cold, Flu, & Sore Throat? Think I have a sinus infection.
I have a sinus headache due to a cold. I took a 24 hour claritin pill this morning, but it didnt help. Can i take benadryl (diphenhydramine) now? Its only been 12 hrs.
Is it okay to take Benadryl (diphenhydramine) after taking a Advil cold & sinus medicine ?

Telemedicine

Primary Care
Manage Your Conditions
Women's Health
Children's Health
Men's Health
Senior Health
Wellness, Prevention & Lifestyle
Sexual Health
Mental & Behavioral Health
Travel Medicine
Urgent Care
Ask your question
Didn't find what you're looking for?

90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more.

Ask your question

More of what we treat

Allergies
Antibiotics
Asthma
High Blood Pressure
Prescriptions
Type 2 Diabetes
Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.
HealthTap
HIPAA logo
HIPAASecure
Soc 2 Type 2 logo
SOC 2 Type 2Certified
JCAHO Accredited
JCAHOAccredited
Member App

Download HealthTap

Video visit and message your doctor

Member App QR Code
Play Store Member LinkApp Store Member Link

Questions?

+1 (888) 828-0841support@healthtap.com
LinkedInTwitter
HomeTermsPrivacyCookiesDMCAHealth TopicsDoctors DirectoryDoctor Q&A by Specialty
Copyright 2026 HealthTap, Inc.