A 38-year-old male asked:
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Is it safe to take sam-e with nsaids?

1 doctor answer
Dr. James Eyerman
46 years experience in Psychiatry
Pharmacy check: Safety Information on the long-term safety of SAMe is limited because the participants in most studies took it only for short periods of time. However, in one study of alcohol-related liver disease, participants took SAMe for 2 years; in that study, no serious side effects were reported. Your pharmacy will be able to check out any interactions with an uptodate data base.
Answered on Mar 11, 2015
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