The most common: cause of circumoral numbness in clinical practice is hyperventilation syndrome (in which the tingling of the lips is accompanied by parasthesias in the hands and feet. It is what occurs with respiratory alkalosis from "blowing off" too much of your carbon dioxide. Ingesting Tetrodotoxin from the Asian Puffer fFsh can also produce circumoral parasthesias as can small strokes or MS (uncommon)
Answered 5/18/2016
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