A member asked:

If genetic testing confirms you are an ultra rapid metabolizer (say of 2d6), what antidepressant choices do you have, if any? or are you out of luck?

2 doctors weighed in across 2 answers

There are choices: There are antidepressants that are not metabolized by 2D6. Zoloft, Celexa, Lexapro, (escitalopram) Luvox are a few. However, knowing that you are an ultrarapid metabolizer does not mean that you may not benefit from medications metabolized by 2D6, it just means that you will require higher than average doses.

Answered 3/8/2015

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Dr. Paul Pyles answered

Specializes in Addiction Medicine

Several options: See your doctor for an evaluation and discussion of your treatment options. Being an ultra rapid metabolizer at 2D6 means that your body clears the medication more rapidly. It may require a higher dose of medication to obtain a therapeutic response. It doesn't mean that the medication can't be tried and it certainly doesn't mean you are out of luck. You have several options. See your doctor.

Answered 3/8/2015

3.1k views

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