A 22-year-old female asked:
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is it ok to combine spironolactone, zantac, (ranitidine) and tmp/smx? i have normal renal function, could this be bad for my potassium levels?

1 doctor answer
Dr. Sean Mirk
Dr. Sean Mirk answered
13 years experience Pharmacology
Combo can increase K: Both spironolactone and trimethoprim-sulfamethoxazole can cause hyperkalemia and the combination should be avoided whenever possible.
Answered on Mar 7, 2015
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