A member asked:

What do you think? ana-positive, titer >1:640, speckled/ana titer 2-1:32, ana pattern 2-homogeneous c3 180.8, rnpab, igg 1.5, crp 1.9.

A doctor has provided 1 answer

Possible MCTD: The highly positive ANA in a speckled pattern suggests mixed connective tissue disease. Mctd is a close cousin of lupus but usually has a better prognosis. The anti-rnp is usually be elevated in mctd. Interpreting the results of autoantibody studies can confusing. You should discuss these findings with a rheumatologist.

Answered 10/15/2017

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