A 67-year-old female asked:
Mcrc pt - chemo fails . what can be done if anything ?
1 doctor answer • 1 doctor weighed in
Surgical Oncology 64 years experience
Immunotherapy trial: At some point chemotherapy fails in patients with met. colorectal Ca. The Ca stem cells in the tumor are resistant to all forms of chemo having DNA repair mechanisms for protection. Immunotherapy with Avastin, (bevacizumab) Erbitux and Neo-101 can help. The latter targets a post translational modification of MUC5ac that acts as an immunogen and is in FDA trails. A newer mAb Neo -201 is being produced.
3.2k viewsAnswered >2 years ago
Last updated Feb 22, 2015
Connect with a U.S. board-certified doctor by text or video anytime, anywhere.
24/7 visits - just $39!
50% off with $15/month membership
Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.