A member asked:

I found out i am a carrier of familial mediterranean syndrom. is it possible to have mild symptoms from the mutation?

A doctor has provided 1 answer
Dr. Roy Arnold answered

Specializes in Internal Medicine

Yes: Although it requires two copies of the FMF gene for full expression, some carriers may have milder forms of the disease. Common symptoms are: Intermittent episodes of fever with robust interim health; Concomitant serositis with abdominal pain and tenderness or pleuritis; Absence of an alternative cause; Responsiveness to colchicine; Monoarthritis Thanks for trusting HealthTap!

Answered 2/18/2015

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