Can i take klonopin (clonazepam) 5mg a few hours after butalb acetaminophen calf 50 325 40mg?

Do you mean 0.5 mg.: 5 mg of Klonopin (clonazepam) is too much but a 0.5 mg. is alright particularly if you have a brain lesion. If in doubt, please call your primary care physician to be safe.

You can: There should be no problem if you take the prescribed doses

Maybe: Butalbital and clonazepam are both sedatives so it's possible the combination could cause excessive sleepiness or confusion. Be careful and consult with whoever is prescribing them.