Can someone have normal blood test and urine test and still have kidney issues ?

Rarely: although it is uncommon one can have her reduced level of kidney function with normal blood and urine test. This is most common in older patients with decreased muscle mass and also with people of small stature or small frame. Their kidney function is better assessed by doing a 24 hour urine collection protein and creatinine clearance. Imaging test are also useful such as kidney ultrasound