Can high gad-65 autoantibodies cause glutamate metabolism disorder (gmd)? what tests confirm gmd? my plasma ammonia is normal & anti-gad ab's high

Can cause diabetes.: It seems these autoabs can cause stiff man's syndrome, a neurological disorder with impaired motor function and muscle stiffness and spasm. There is also a great deal of glutamic acid decarboxylase in the pancreas and so these antibodies act here and produce diabetes mellitus in the patient. This is likely the metabolic disorder involved. So titers of this ab, glucose, and neural tests help.