A member asked:

When tumors secrete high levels of vasopressin, what happens to plasma osmolarity, urine osmolarity and urine volume ?

6 doctors weighed in across 2 answers

SIADH: Plasma osmolarity will decrease, urine osmolarity will increase, and urine volume will decrease.

Answered 5/18/2013

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Tricky concept: ADH / vasopressin makes the body reabsorb water. However, the atrial natriuretic peptide then kicks in and rids the body of that water by forcing excretion of sodium in the urine. Low plasma sodium / lowish osmolarity; urine sodium will be inappropriately high.

Answered 6/10/2014

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