Creatinine level is 3.9, leukocytes 3-5, erthrocytes 10-12 protein ++ in urine. could it be my medications?

Unlikely: You have blood and protein in your urine. With poor function. The blood vessels in the kidney filters have damage to their walls allowing for the loss of blood and protein from the blood stream into the urine. This is also called a glomerulonephritis. Possible causes IgA nephropathy, lupus, wegeners, and others. You need to see a kidney doctor for diagnosis. Medications should not cause this.

High creatinine: You should see a nephrologist to get answer to your question. Some medicines, of the advil (ibuprofen) class, can cause acute renal failure, which reverses once you stop taking them. Due to the presence of protein and blood in your urine, you need a 24 hour urine collection for creatinine clearance and protein. You also need some blood work to see if you have diseases that can cause proteinuria, diabetes?