Zioptan is safe: Zioptan is another addition to a successful class of antiglaucoma medications with a very favorable safety profile. Most anti-glaucoma medications lose effectiveness because of the progression of the underlying disease. Probably in some cases it is due to some degree of resistance to the medication but this is a less likely cause. Regular checkups are mandatory.
Answered 3/25/2013
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Safe: Zioptin is safe, as long as you do not have an allergy to any of the components in the drop. Drops and their affects can become less with long term use, this typically only happens with beta blocker drops. It is possible the pressure became more difficult to control due to the underlying cause, instead of the drops not working.
Answered 12/10/2013
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