Had boxers fracture in splint for 14 days. can i take off splint and buddy splint and wrap my metacarpal bones 2-5 in self adherent wrap?

Depends on healing: I do allow buddy taping of the 5th and 4th fingers for a 5th metacarpal fracture once the fracture has stabilized. Fracture stability is indicated by lack of new displacement and angulation plus the presence of new bone on the x-rays, indicating healing.

Sometimes: Usually that can be enough time to switch to taping, however suggest xrays and exam first. Don't do it yourself.